Publications

A. K. L. Wezenaar, U. Pandey, F. Keramati, M. Hernandez-Roca, Peter Brazda, M. Barrera Román, A. Cleven, F. Karaiskaki, T. Aarts-Riemens, S. de Blank, P. Hernandez-Lopez, S. Heijhuurs, A. Alemany, J. Kuball, Z. Sebestyen, J. F. Dekkers, H. G. Stunnenberg, M. Alieva, A. C. Rios (2025). Mapping T cell dynamics to molecular profiles through behavior-guided transcriptomics. Nature Protocols.

Michael Rade, David Fandrei, Markus Kreuz, Sabine Seiffert, Thomas Wiemers, Patrick Born, Luise Fischer, Heike Weidner, Lorenz Hofbauer, Ronny Baber, Song-Yau Wang, Enrica Bach, Sandra Hoffmann, Jonathan Scolnick, Mirco Friedrich, Farid Keramati, Peter Brazda, Zsolt Sebestyen, Jürgen Kuball, Klaus Metzeler, Marco Herling, Carmen Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Andreas Boldt, Anja Grahnert, Maik Friedrich, Ulrike Köhl, Uwe Platzbecker, Vladan Vucinic, Kristin Reiche, Maximilian Merz (2025). A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma. Research Square Preprint.

Peter Brazda, Astrid Cleven *, Angelo D. Meringa *, Domenico Fasci, Thijs Koorman, Tineke Aarts, Inez Johanna, Dennis X Beringer, Patricia Hernandez-Lopez, Sabine Heijhuurs, Tomohiro Mizutani, Sangho Lim, Maarten Huismans, Jochem Bernink, David Vargas Diaz, Wei Wu, Esther San Jose, Jelle Schipper, Nikos Tsakirakis, Lauren Hoorens van Heyningen, Annick Nouwens, Lucrezia Gatti, Trudy Straetemans, Hugo Snippert, Jeanine Roodhart, Patrick W.B. Derksen, Jarno Drost, Maarten Altelaar, Albert J.R. Heck, Hans Clevers, Juergen Kuball, Zsolt Sebestyen (2024). Sensitivity to Vg9Vδ2TCR T cells is imprinted after single mutations during early oncogenesis. bioRxiv.

Joshua Gillard, Madeleine Suffiotti, Peter Brazda, Prashanna B. Venkatasubramanian, Pauline Versteegen, Marien I. de Jonge, Dominic Kelly, Sagida Bibi, Marta Valente Pinto, Elles Simonetti, Mihaela Babiceanu, Andrew Kettring, Cristina Teodosio, Ronald de Groot, Guy Berbers, Hendrik G. Stunnenberg, Brian Schanen, Craig Fenwick, Martijn A. Huynen, Dimitri A. Diavatopoulos (2024). Antiviral responses induced by Tdap-IPV vaccination are associated with persistent humoral immunity to Bordetella pertussis. Nature Communications.

Patricia Hernandez-Lopez, Eline van Diest, Peter Brazda, Sabine Heijhuurs, Angelo Meringa, Lauren Hoorens van Heyningen, Caterina Riillo, Caroline Schwenzel, Marina Zintchenko, Inez Johann, Mara J. T. Nicolasen, Astrid Cleven *, Thomas A. Kluiver, Rosemary Millen, Jiali Zheng, Froso Karaiskaki, Trudy Straetemans, Hans Clevers, Remco de Bree, Hendrik G. Stunnenberg, Weng Chuan Peng, Jeanine Roodhart, Susana Minguet, Zsolt Sebestyen, Dennis X. Beringer, Jürgen Kuball (2023). Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells. Nature Immunology.

Bálint Rehó, Lina Fadel, Peter Brazda, Anass Benziane, Éva Hegedüs, Pialy Sen, Theodorus W.J. Gadella, Katalin Toth, Laszlo Nagy, Gyorgy Vamosi (2023). Agonist-controlled competition of RAR and VDR nuclear receptors for heterodimerization with RXR is manifested in their DNA-binding. Journal of Biological Chemistry.

Nader Atlasy, Anna Bujko, Espen S Bækkevold, Peter Brazda, Eva Janssen-Megens, Knut E A Lundin, Jørgen Jahnsen, Frode L Jahnsen, Hendrik G Stunnenberg (2022). Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease. Nature Communications.

Peter Brazda, Cristian Ruiz-Moreno, Wout Megchelenbrink, Henri J L M Timmers, Hendrik G Stunnenberg (2022). Extensive patient-to-patient single nuclei transcriptome heterogeneity in pheochromocytomas and paragangliomas. Frontiers in Oncology.

Yanan Zhai, Prashant Singh, Anna Dolnik, Peter Brazda, Nader Atlasy, Nunzio del Gaudio, Konstanze Döhner, Hartmut Döhner, Saverio Minucci, Joost Martens, Lucia Altucci, Wout Megchelenbrink, Lars Bullinger, Hendrik G. Stunnenberg (2022). Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia. Molecular Cancer.

Johanna F Dekkers, Maria Alieva, Astrid Cleven *, Farid Keramati, Peter Brazda, Heggert G Rebel, Amber KL Wezenaar, Jens Puschhof, Maj-Britt Buchholz, Mario Barrera Román, Inez Johanna, Angelo D. Meringa *, Domenico Fasci, Maarten H. Geurts, Hendrikus C.R. Ariese, Esmée J. van Vliet, Ravian L. van Ineveld, Effrosyni Karaiskaki, Oded Kopper, Yotam E. Bar-Ephraim, Kai Kretzschmar, Alexander M.M. Eggermont, Ellen J. Wehrens, Henk G. Stunnenberg, Hans Clevers, Jürgen Kuball, Zsolt Sebestyen, Anne C. Rios (2022). Uncovering the mode of action of engineered T cells in patient cancer organoids. Nature Biotechnology.

Hendrik G Stunnenberg, Cristian Ruiz-Moreno, Farid Keramati, Peter Brazda, Wout Megchelenbrink, Brigit te Pas, Kim Boshuisen, Helena C Besse, Lennart Kester, Mariette Kranendonk (2021). Reprogramming of pro-tumor macrophages by hydroxychloroquine in an abdominally metastasized diffuse midline glioma. medRxiv.

Bálint Rehó, Lukas Lau, Gábor Mocsár, Gabriele Müller, Lina Fadel, Peter Brazda, Laszlo Nagy, Katalin Toth, Gyorgy Vamosi (2019). Simultaneous mapping of molecular proximity and comobility reveals agonist-enhanced dimerization and DNA binding of nuclear receptors. Analytical Chemistry.

Roberta Martinelli, Gurdyal S. Besra, Petr A. Illarionov, Istvan Szatmari, Peter Brazda, Mary A. Allen, Wenqing Xu, Xiang Wang, László Nagy, Robin D. Dowell, Graham A. W. Rook, Laura Rosa Brunet, Christopher A. Lowry David G. Smith (2019). Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties. Psychopharmacology.

Peter Brazda, Charl Moolman, Jacob Kerssemakers, Belen Solano, Nynke Dekker Roy de Leeuw (2017). Measuring In Vivo Protein Dynamics Throughout the Cell Cycle Using Microfluidics. The Bacterial Nucleoid: Methods and Protocols (Methods in Molecular Biology).

Peter Brazda (2014). Determination of dynamic properties of nuclear receptors. PhD Thesis.

Jan W Krieger, Agata Pernus, Peter Brazda, Jörg Langowski (2014). Protein Interaction and Transport Maps of Live Cell Nuclei Using Fluorescence Correlation Spectroscopy in a Single Plane Illumination Microscope. Microscopy and Microanalysis.

Peter Brazda, Jan Krieger, Bence Daniel, David Jonas, Tibor Szekeres, Jörg Langowski, Katalin Toth, Laszlo Nagy, Gyorgy Vamosi (2014). Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging. Molecular and cellular biology.

P Brazda, B Reho, J Krieger, K Toth, L Nagy, G Vamosi (2013). Activation enhances DNA-binding of RXR but not the number of binding sites as shown by FCS/ChIP-seq. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS.

Katalin Toth, Zsolt Sarang, Beáta Scholtz, Peter Brazda, Norbert Ghyselinck, Pierre Chambon, László Fésüs, Zsuzsa Szondy (2011). Retinoids enhance glucocorticoid-induced apoptosis of T cells by facilitating glucocorticoid receptor-mediated transcription. Cell Death & Differentiation.

Peter Brazda, Tibor Szekeres, Balazs Bravics, Katalin Toth, Gyorgy Vamosi, Laszlo Nagy (2011). Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility. Journal of cell science.

Peter Brazda, Tibor Szekeres, Balazs Bravics, Katalin Toth, Laszlo Nagy, Gyoergy Vamosi (2011). Dissecting the role of coregulator exchange and chromatin binding in retinoic acid receptor (RAR) mobility by live cell FCS. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS.

Balint L Balint, Ophir Keret, Peter Brazda, Mate Demeny, others (2010). Building Protein Domain Based Composite Biobricks for Mammalian Expression Systems.

Gy Vamosi, P Brazda, T Szekeres, T Domoszlai, A Horvath, K Toth, S Damjanovich, L Nagy (2009). Nuclear receptor activation viewed via mobility. ACTA PHYSIOLOGICA HUNGARICA.

Gyorgy Vamosi, Nina Baudendistel, Claus-Wilhelm Von der Lieth, Nikoletta Szalóki, Gábor Mocsár, Gabriele Müller, Peter Brazda, Waldemar Waldeck, Sándor Damjanovich, Jörg Langowski, others (2008). Conformation of the c-Fos/c-Jun complex in vivo: A combined FRET, FCCS, and MD-modeling study. Biophysical journal.

Peter Brazda, Tibor Szekeres, Balazs Bravics, Katalin Toth, Laszlo Nagy, Gyorgy Vamosi (2007). A transzkripciós szabályozás dinamikus arca / The dynamic face of transcriptional regulation. Biokemia (in Hungarian).

Istvan Szatmari, Gyorgy Vamosi, Peter Brazda, Balint L Balint, Szilvia Benko, Lajos Széles, Viktoria Jeney, Csilla Özvegy-Laczka, Attila Szántó, Endre Barta, others (2006). Peroxisome proliferator-activated receptor γ-regulated ABCG2 expression confers cytoprotection to human dendritic cells. Journal of Biological Chemistry.

P Brazda, S Benko, L Nagy (2005). Characterization of a novel retinoid-x receptor antagonist, LG1208: K3-011P. The Febs Journal.