2

Determination of dynamic properties of nuclear receptors
We characterized and compared the nuclear dynamics of RXR and RAR during activation in single cells on the sub-second scale using …
Peter Brazda
PDF Cite
Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging
Retinoid X receptor (RXR) is a promiscuous nuclear receptor forming heterodimers with several other receptors, which activate different …
Peter Brazda, Jan Krieger, Bence Daniel, David Jonas, Tibor Szekeres, Jörg Langowski, Katalin Toth, Laszlo Nagy, Gyorgy Vamosi
PDF Cite
Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging
Protein Interaction and Transport Maps of Live Cell Nuclei Using Fluorescence Correlation Spectroscopy in a Single Plane Illumination Microscope
Proteins acting on DNA need to penetrate a dense network of chromatin and associated macromolecules in the cell nucleus to access their …
Jan W Krieger, Agata Pernus, Peter Brazda, Jörg Langowski
PDF Cite
Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility
The retinoic acid receptor (RAR) is a member of the nuclear receptor superfamily. This ligand-inducible transcription factor binds to …
Peter Brazda, Tibor Szekeres, Balazs Bravics, Katalin Toth, Gyorgy Vamosi, Laszlo Nagy
PDF Cite
Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility
Retinoids enhance glucocorticoid-induced apoptosis of T cells by facilitating glucocorticoid receptor-mediated transcription
Glucocorticoid-induced apoptosis of thymocytes is one of the first recognized forms of programmed cell death. It was shown to require …
Katalin Toth, Zsolt Sarang, Beáta Scholtz, Peter Brazda, Norbert Ghyselinck, Pierre Chambon, László Fésüs, Zsuzsa Szondy
PDF Cite
Conformation of the c-Fos/c-Jun complex in vivo: A combined FRET, FCCS, and MD-modeling study
Gyorgy Vamosi, Nina Baudendistel, Claus-Wilhelm Von der Lieth, Nikoletta Szalóki, Gábor Mocsár, Gabriele Müller, Peter Brazda, Waldemar Waldeck, Sándor Damjanovich, Jörg Langowski, others
Cite
Peroxisome proliferator-activated receptor γ-regulated ABCG2 expression confers cytoprotection to human dendritic cells
ABCG2, a member of the ATP-binding cassette transporters has been identified as a protective pump against endogenous and exogenous …
Istvan Szatmari, Gyorgy Vamosi, Peter Brazda, Balint L Balint, Szilvia Benko, Lajos Széles, Viktoria Jeney, Csilla Özvegy-Laczka, Attila Szántó, Endre Barta, others
PDF Cite
Characterization of a novel retinoid-x receptor antagonist, LG1208: K3-011P
P Brazda, S Benko, L Nagy
Cite