2

Antiviral responses induced by Tdap-IPV vaccination are associated with persistent humoral immunity to Bordetella pertussis
Many countries continue to experience pertussis epidemics despite widespread vaccination. Waning protection after booster vaccination …
Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells
Few cancers can be targeted efficiently by engineered T cell strategies. Here, we show that γδ T cell antigen receptor (γδ …
Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia
Background Acute myeloid leukemia (AML) is a heterogeneous and aggressive blood cancer that results from diverse genetic aberrations in …
Uncovering the mode of action of engineered T cells in patient cancer organoids
Extending the success of cellular immunotherapies against blood cancers to the realm of solid tumors will require improved in vitro …
Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties
RATIONALE: Mycobacterium vaccae (NCTC 11659) is an environmental saprophytic bacterium with anti-inflammatory, immunoregulatory, and …